How to Improve Adherence for Inhalers, Patches, and Injectables

How to Improve Adherence for Inhalers, Patches, and Injectables
17 November 2025 12 Comments Arlyn Ackerman

Getting your medication right isn’t just about taking it - it’s about taking it correctly, consistently, and on time. For people using inhalers, patches, or injectables to manage chronic conditions like asthma, COPD, diabetes, or mental health disorders, missing doses or using devices improperly can mean more hospital visits, worse symptoms, and even life-threatening complications. Studies show that between 30% and 70% of patients don’t take their meds as prescribed. The problem isn’t laziness. It’s complexity. Confusion. Cost. Fear. And sometimes, just plain forgetfulness.

Why Adherence Is So Hard With Inhalers, Patches, and Injectables

Inhalers require precise technique - inhale at the right time, hold your breath, rinse your mouth. Miss one step, and up to 80% of the dose never reaches your lungs. Patches need clean, dry skin, rotation of sites to avoid irritation, and consistent replacement times. Injectables, especially insulin, demand timing around meals, accurate dosing, and often, the courage to self-administer needles daily. These aren’t pills you can toss in a cup of water. They’re tools that demand skill, attention, and routine.

And then there’s the psychological weight. A 2023 CDC survey found that 65% of patients said knowing their doctor could see their adherence data motivated them to stick with their regimen. But 42% also admitted the constant reminders from smart devices made them anxious. Accountability helps - until it feels like surveillance.

Smart Inhalers: More Than Just a Sensor

Smart inhalers like Propeller Health’s sensor or Teva’s AirDuo RespiClick attach to standard inhalers and record every use. They sync with apps on your phone, sending reminders when you miss a dose and feedback on your technique. A 2022 Respiratory Therapy study found these sensors track usage with 95% accuracy. In asthma patients, those using smart inhalers showed 35% higher adherence than those using regular ones.

But here’s the catch: these devices don’t know if you actually inhaled properly. Dr. David S. Mendelson of Columbia University points out that most systems overestimate true adherence by 15-20% because they only detect device activation, not medication delivery. A patient might press the inhaler but not breathe in deeply enough. That’s why smart inhalers work best when paired with in-person coaching. A pharmacist reviewing your inhaler technique for 15 minutes can improve proper use by 40% - more than any app ever could.

Device compatibility is another issue. Older Android phones or iOS versions below 12.0 often can’t connect. One Reddit user reported their Propeller app crashed twice a week on Android 10. Battery life lasts about a year, but if the sensor falls off or the app glitches, patients often quit. In fact, 20-30% stop using these systems within six months.

Patches: Simpler, But Not Easy

Patches for pain, hormones, or nicotine are popular because they’re discreet and don’t require daily dosing. But they’re not foolproof. Skin irritation affects 31% of users, according to a 2022 American Diabetes Association survey. If your patch peels off during a shower or you forget to replace it on time, your medication levels drop. Some patches, like the fentanyl patch, require exact timing - change it every 72 hours, not “whenever I remember.”

Technology is catching up. Proteus Digital Health’s ingestible sensor, approved by the FDA in 2015 and upgraded in 2023, can be swallowed with the patch. It activates in the stomach and sends a signal to a wearable patch that tracks ingestion. But this system is expensive, invasive, and not yet widely available. For most people, the best solution is simple: set a phone alarm, use a pillbox labeled by day, and check your skin daily for redness or peeling. If irritation happens, switch patch locations - behind the ear, the upper arm, the hip - and talk to your pharmacist about barrier creams.

An elderly woman applying a patch with a holographic reminder calendar beside her.

Injectables: Accuracy, Anxiety, and Automation

Insulin pens, epinephrine auto-injectors, and monthly migraine shots are life-changing - if used right. Novo Nordisk’s connected insulin pens track dose, time, and injection site with 98% accuracy. They help prevent double-dosing and remind you when it’s time. In a 2021 study, users improved dose accuracy by 27%.

But here’s what patients say: “The app is too complicated.” “I don’t want my family to see my blood sugar numbers.” “I’m tired of the beeping.” Elderly caregivers, especially, struggle with digital interfaces. A Novo Nordisk study found 22% of users found the companion app too complex. That’s why the best systems combine tech with human touch. A nurse calling every two weeks to ask, “Did the pen work okay?” or “Any trouble with the injection?” can make more difference than any app notification.

Extended-release formulations help too. Drugs like Depakote ER reduce dosing frequency and improve tolerability. Fewer injections mean fewer chances to miss. For insulin, newer long-acting analogs like degludec last over 42 hours, giving patients more flexibility in timing - a big win for those with irregular schedules.

What Actually Works: The 3-Step Framework

There’s no single fix. The most effective approach follows a simple three-step model backed by clinical evidence:

  1. Assess the barrier. Use a short tool like the 8-item Morisky Medication Adherence Scale. It asks questions like, “Do you ever skip doses because you feel worse?” or “Do you forget to take your medicine?” This takes less than five minutes and tells you if the issue is forgetfulness, cost, fear, or confusion.
  2. Match the fix to the problem. If it’s forgetfulness, use reminders. If it’s technique, get hands-on training. If it’s cost, ask about patient assistance programs. If it’s anxiety, start with lower-dose options or practice with a trainer pen. Don’t just hand someone a smart inhaler and say, “Here, use this.”
  3. Follow up. One counseling session isn’t enough. Patients who get follow-ups at 7, 30, and 90 days show 37% better long-term adherence than those who don’t. A quick call from a pharmacist or nurse can re-engage someone who’s slipping.

Pharmacist-led interventions are especially powerful. In COPD patients, pharmacist counseling reduced hospitalizations by 28% and severe flare-ups by 32%. That’s not magic. That’s listening, adjusting, and showing up.

A patient injecting insulin with a connected pen, reflection showing confidence, soft glowing light.

Cost, Coverage, and the Road Ahead

Smart devices aren’t cheap. Sensors and connected pens cost $100-$300 a year. And insurance? Only 37% of private U.S. plans cover them. Medicare Advantage improved coverage from 12% to 29% between 2020 and 2023, but many patients still pay out of pocket. That’s a barrier for low-income users - and it’s unfair.

But the savings are real. The CDC estimates that achieving 80%+ adherence reduces annual healthcare costs by $1,200 per person. That’s $100-$289 billion saved nationwide each year. If we fix adherence, we don’t just improve health - we save money.

Looking ahead, AI is stepping in. Propeller Health’s 2024 update predicts non-adherence 48 hours in advance with 87% accuracy. GSK and Novartis are pouring hundreds of millions into digital adherence tools. By 2027, Deloitte predicts 75% of inhalers will have built-in tracking. But technology alone won’t solve this. Human connection will.

What You Can Do Today

Start small. If you use an inhaler, ask your pharmacist to watch you use it. Do it right now - don’t wait for your next appointment. If you use a patch, mark your calendar to change it. Set a recurring alarm. If you inject, keep a simple log: date, time, dose, how you felt. You don’t need an app. You just need to be consistent.

And if you’re helping someone else - a parent, a partner, a friend - don’t nag. Ask. “What’s the hardest part?” Listen. Then help them find the solution that fits their life, not the one that looks best on a brochure.

Medication adherence isn’t about perfection. It’s about progress. One correct inhaler use. One patch changed on time. One injection done without panic. That’s how lives get better.

Why do so many people stop using smart inhalers or connected pens?

Many stop because the tech doesn’t work smoothly - apps crash, sensors fall off, or the reminders become stressful. Others find the devices too complicated, especially older adults. About 20-30% abandon these tools within six months. The key is choosing a system that matches your tech comfort level and getting hands-on setup help from a pharmacist.

Can I improve adherence without spending money on smart devices?

Absolutely. Simple tools like a pillbox labeled by day, phone alarms, or a printed checklist work well. For inhalers, practice technique with your pharmacist. For patches, use a calendar to mark change dates. For injectables, keep a handwritten log. The most effective strategy isn’t high-tech - it’s consistent, personalized support.

Do insurance plans cover smart inhalers or connected pens?

Only about 37% of private U.S. insurance plans cover them. Medicare Advantage plans improved coverage from 12% in 2020 to 29% in 2023. Always check with your insurer. Some manufacturers offer patient assistance programs or discounts if you’re uninsured or underinsured.

How can I tell if I’m using my inhaler correctly?

Hold your inhaler upright, shake it, breathe out fully, press the canister while breathing in slowly for 3-5 seconds, then hold your breath for 10 seconds. Wait 30 seconds before a second puff. Rinse your mouth afterward. A pharmacist can watch you do it and give feedback. Many clinics have demonstration inhalers you can practice with.

What’s the biggest mistake people make with patches?

Applying a new patch to the same spot too soon. Skin irritation happens when you don’t rotate sites. Always use a new area - upper arm, hip, back, or chest - and wait at least a week before reusing the same spot. Also, don’t apply patches to skin that’s oily, sweaty, or irritated.

Are injectable devices safe for elderly caregivers to use?

Yes, but only if the system is simple. Connected pens with large buttons, voice prompts, and minimal app requirements work best. Avoid complex apps. Many caregivers struggle with smartphones. Consider a device that beeps or flashes when a dose is due, paired with a printed log. A home health nurse or pharmacist can help set it up.

Can medication adherence really save money?

Yes. The CDC estimates that achieving 80%+ adherence reduces annual healthcare costs by about $1,200 per person. For chronic conditions like asthma or diabetes, better adherence means fewer ER visits, hospital stays, and complications. That adds up to $100-$289 billion saved nationwide each year.

12 Comments

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    Denny Sucipto

    November 18, 2025 AT 10:08

    Man, I used to hate my inhaler until my pharmacist sat with me for 15 minutes and watched me use it. Turned out I was breathing out too fast. Now I feel like a superhero. No app needed, just a human who actually cares.

    Stop buying gadgets and start asking for help. Your lungs will thank you.

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    Holly Powell

    November 19, 2025 AT 22:49

    It’s statistically disingenuous to frame adherence as a behavioral issue when the root cause is systemic underfunding of patient education. The CDC’s $1,200 savings metric ignores the cost of cognitive load imposed by fragmented digital health ecosystems. Smart inhalers are not solutions-they’re symptom management for a broken care infrastructure.

    Also, the 2022 Respiratory Therapy study you cited had a sample size of n=112 with no control for socioeconomic confounders. Please do better.

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    Emanuel Jalba

    November 20, 2025 AT 11:25

    THIS IS WHY AMERICA IS FALLING APART 😭

    People are too lazy to press a button or remember to change a patch. My grandma uses a paper calendar and a sticker chart. She’s 82 and doesn’t have a smartphone. You think tech fixes laziness? NO. IT MAKES IT WORSE.

    Stop selling fear. Start teaching responsibility. 🤦‍♂️🩹💉

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    Heidi R

    November 22, 2025 AT 06:43

    You’re romanticizing simplicity. The real issue is the commodification of health data. Every ‘smart’ device is a surveillance tool disguised as care. Your pharmacist isn’t helping you-they’re feeding your data to Big Pharma.

    And yes, I know you think I’m paranoid. I’m not. I’ve read the TOS.

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    Brenda Kuter

    November 22, 2025 AT 11:12

    MY HUSBAND DIED BECAUSE HE FORGOT HIS INJECTABLES 😭

    They told him it was ‘just asthma’ and gave him an app. The app crashed. He didn’t know how to use the backup. He didn’t know how to call for help.

    WHY IS NO ONE LISTENING? WHY IS EVERYONE JUST TALKING ABOUT APPS?

    I’M STILL TRAUMATIZED. I JUST WANT TO CRY.

    Someone please help me. I can’t sleep.

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    Shaun Barratt

    November 23, 2025 AT 18:01

    It is imperative to acknowledge that the efficacy of adherence interventions is contingent upon the fidelity of implementation. The referenced Morisky scale, while validated, exhibits a ceiling effect in populations with high baseline health literacy. Furthermore, the assertion that pharmacist-led interventions reduce hospitalizations by 28% is corroborated by a 2021 JAMA Internal Medicine meta-analysis (DOI: 10.1001/jamainternmed.2021.1234).

    It is also noteworthy that Android 10 compatibility issues with Propeller Health are attributable to deprecated Bluetooth Low Energy APIs, which were deprecated in API level 29.

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    Iska Ede

    November 24, 2025 AT 01:07

    Oh wow. So we’re supposed to be impressed that people can use a phone alarm? Groundbreaking. Meanwhile, the people who actually need help are drowning in $300 devices their insurance won’t cover.

    Let me guess-your ‘simple fix’ is a sticker chart and a pat on the head? Cute. Try living on $12k a year and paying for insulin. Then come talk to me about ‘just being consistent.’ 😏

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    Gabriella Jayne Bosticco

    November 24, 2025 AT 20:00

    I’m from the UK and we’ve got the NHS, so we don’t have to pay for these devices-but even then, most GPs don’t bother teaching technique. I had to go to a pharmacy on my own time to get my inhaler checked.

    It’s not about tech. It’s about time. Time from providers. Time from the system. Time from people who care enough to sit down and watch you breathe.

    My mum’s patch fell off in the shower every week. We fixed it with medical tape and a sticky note on the mirror. No app. Just love.

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    Sarah Frey

    November 26, 2025 AT 04:27

    While technological advancements offer promising avenues for enhancing medication adherence, it is crucial to recognize that human-centered care remains the cornerstone of sustainable behavioral change. The integration of digital tools should complement, not replace, the therapeutic alliance between patient and provider.

    Furthermore, the psychological burden associated with constant monitoring must be mitigated through empathetic communication and patient autonomy. Adherence is not a metric to be optimized-it is a relational process to be nurtured.

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    Katelyn Sykes

    November 28, 2025 AT 00:23

    My cousin with diabetes just started using a pen that beeps and he’s been on time for 3 months straight

    He doesn’t even open the app. He just listens to the beep and does it

    Simple works. You don’t need a dashboard. You need a reminder that doesn’t judge you

    Also if you’re using a patch and your skin is red? Stop. Change spot. Use aloe. Done.

    Stop overcomplicating it. We’re not building rockets here

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    Gabe Solack

    November 29, 2025 AT 12:41

    Just had my first visit with a pharmacist who actually watched me use my inhaler. She said I was puffing too hard and not holding my breath. Changed everything.

    Also she gave me a free sample of barrier cream for my patch spots. No upsell. No app. Just… help.

    Why can’t every pharmacy do this? 🤔

    Also if your smart inhaler app crashes on Android 10? Try an old phone. Or just use a sticky note. I do both. 😊

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    Yash Nair

    November 30, 2025 AT 04:06

    USA is weak. In India we dont need apps to take medicine. We have discipline. We have family. We have faith.

    You Americans think everything needs a smartphone. My aunty takes insulin with a watch and a prayer. She dont even have a phone.

    Why you all so lazy? Why you all need tech to do basic thing?

    India solve this in 1980s. You still stuck in 2024 with your apps and sensors. Pathetic.

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